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Tg(Thyroglobulin) Antigen Elisa kit for IVD use

Thyroglobulin (TG) is a high MW (ca. 650-700 kDa) glycoprotein synthesized  by the thyroid epithelial cells. In normal thyroid gland, TG is secreted to the follicular lumen and undergoes iodination of tyrosine residues leading to formation of thyroid hormones (T3 and T4). Minor quantities of TG penetrate to the circulation in normal donors. Synthesis of TG is regulated by hormones (TSH, TRH, exogenous thyroid therapy). In differentiated thyroid carcinoma, serial determination of serum TG is used for post-treatment monitoring. An elevation of serum TG in such patients indicates a presence of residual thyroid tissue, relapse or metastatic growth of the tumour. The elevated serums TG are also observed in benign thyroid diseases, e.g. thyroiditis, hyperthyroidism and non-toxic goiter. The monitoring of serum TG is also used for prognostic evaluation of thyrostatic treatment of Graves’ disease. 

kit is avaiable in 96 wells format..CE certified and IVD use