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aTPO(Thyroid Peroxidase Ab) ELISA Kit for 96 wells

Anti-TPO antibodies (formerly – thyroid microsomal antibodies) are directed against a target protein – thyroid peroxidase (TPO) – located in the smooth endoplasmic reticulum of thyroid cells. The presence of anti-TPO antibodies in serum is associated with thyroid autoimmune diseases (Graves' disease and Hashimoto's thyroiditis). AntiTPO antibodies mostly belong to the IgG class. Low to moderate levels of serum anti-TPO antibodies can be found in some other autoimmune pathology (eg systemic lupus erythematosus or Sjogren syndrom) and, rarely, in apparently healthy subjects (especially elderly women). Anti-TPO antibodies are more sensitive in diagnosis of thyroid autoimmune diseases than anti-thyroglobulin (anti-TG) antibodies. However, in some cases anti-TG positive sera may be negative for anti-TPO. Therefore, combined determination of both types of anti-thyroid antibodies (anti-TPO + anti-TG) provides a more sensitive laboratory diagnostic tool for thyroid autoimmunity. 

kit is CE certified & IVD use